Ofatumumab is used to prevent immune system cells ( lymphocytes ) from attacking the nerves in your brain and spinal cord. Ofatumumab ( Kesimpta ) is an injection you give yourself or get from your doctor every four weeks. Blood counts and liver enzymes should be monitored. Monomethyl fumarate (Bafiertam) is a pill taken twice per day and is similar to dimethyl fumarate. Common side effects include flushing, belly pain, diarrhea, and nausea. The drug is also linked to progressive multifocal leukoencephalopathy (PML), a rare brain infection. Because the medicine may slow your heart rate, the doctor will watch you closely after your first dose. Common side effects include headache, diarrhea, back pain, cough, and abnormal liver tests. If you haven’t had chickenpox, you’ll need a vaccine. Vumerity has been shown to be easier on the stomach than Tecfidera.įingolimod ( Gilenya ) is also a once-daily tablet. Its most common side effects are flushing, redness, itching, rash, nausea, vomiting, diarrhea, stomach pain, or indigestion. The drug is used to treat relapsing forms of MS. An active ingredient similar to the one in Tecfidera is linked to four cases of PML.ĭiroximel fumarate ( Vumerity ) is similar to Tecfidera. The drug's most common side effects are flushing, stomach pain, diarrhea, nausea, and vomiting. It can lower your immune cells, so the doctor will do regular blood tests to keep an eye on them. You could also have hair loss and rashes.ĭimethyl fumarate ( Tecfidera ) is a tablet you take twice a day. It can affect your immune system and make you more likely to get other infections, so you will need to be monitored. It is not for treating relapsing forms of MS, including relapsing-remitting disease and active secondary progressive disease. You can take other medications as a pill:Ĭladribine ( Mavenclad ) is a pill taken once a day for 5 days for a month and once a day again for the second month. Other injectables include Interferon beta-1a (Avonex, Rebif), Interferon beta-1b (Betaseron, Extavia), ofatumumab (Kesimpta), and peginterferon beta-1a (Plegridy). Glatiramer ( Copaxone, Glatopa ): This medication stops your immune system from attacking the myelin that surrounds and protects your nerves. That’s because they lower the number of white blood cells, which help your immune system fight illnesses. They may make you slightly more likely to get an infection. They can also cause flu-like symptoms, like aches, fatigue, fever, and chills, but these should fade within a few months. They make flares less frequent and less severe. They include:īeta interferons: These are some of the most common drugs used to treat MS. The shot might make your skin sore, red, itchy, or dimply. Some drugs come as injections under your skin or into a muscle.
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